8. Comfrey
Comfrey is sometimes promoted as a natural remedy for pain or inflammation, but oral comfrey is generally considered unsafe.
It contains compounds known as pyrrolizidine alkaloids, which have been associated with severe liver injury when consumed. For this reason, comfrey tea, capsules, and other products intended for internal use are generally best avoided unless specifically recommended by a qualified healthcare professional.
9. Turmeric or Curcumin Supplements
Turmeric used as a culinary spice is generally different from concentrated curcumin supplements.
Although uncommon, high-dose turmeric or curcumin supplements have been associated with rare reports of liver injury. The potential risk may be greater with highly concentrated formulations, enhanced-absorption products, or when combined with certain medications or other supplements.
People with existing or previous liver disease should consult a healthcare professional before using concentrated turmeric or curcumin supplements.
Warning Signs Your Liver or Kidneys May Be Struggling
Seek medical advice promptly if you notice yellowing of the skin or eyes, dark urine, pale stools, severe nausea, vomiting, unusual fatigue, abdominal pain, loss of appetite, swelling in the legs or ankles, foamy urine, blood in the urine, confusion, or severe weakness. These symptoms can have many possible causes and should not be ignored.
The liver and kidneys help process many substances that enter the body. Taking multiple supplements, high doses, alcohol, prescription medications, or herbal extracts together may increase the likelihood of side effects or interactions in some people.
Who Should Be Extra Careful?
Extra caution is advised for older adults, pregnant or breastfeeding women, people with kidney disease, liver disease, diabetes, heart disease, high blood pressure, cancer, autoimmune conditions, and anyone taking prescription medications.
It is also wise to be cautious with supplements purchased online, detox products, weight-loss formulas, bodybuilding supplements, and products that promise rapid or dramatic results.
Using supplements wisely often comes down to a few simple habits. These practical tips can help reduce unnecessary risks.