4. Vitamin C in Very High Doses
Vitamin C is a water-soluble vitamin that supports immune function and collagen production. While generally well tolerated, very high supplemental doses may increase urinary oxalate and uric acid levels, which could contribute to kidney stone formation in susceptible individuals.
People with a history of kidney stones, chronic kidney disease, or conditions involving oxalate metabolism may benefit from discussing high-dose vitamin C supplementation with a healthcare professional.
5. Iron Supplements
Iron is essential for producing healthy red blood cells, but supplementation should generally be based on a confirmed deficiency or medical recommendation.
Excessive iron intake can be harmful. Very high doses may lead to serious poisoning, while long-term excess intake may contribute to liver problems, particularly in people with iron overload disorders.
Blood testing is typically recommended before starting iron supplements to determine whether supplementation is necessary.
6. Green Tea Extract
Drinking green tea is different from taking concentrated green tea extract supplements. Concentrated extracts, particularly those found in some weight-loss products, have been associated with rare cases of liver injury.
Anyone who develops symptoms such as yellowing of the skin or eyes, dark urine, abdominal pain, unusual fatigue, nausea, or loss of appetite after taking green tea extract should stop using the product and seek prompt medical advice.
7. Kava
Kava is an herbal supplement commonly used for relaxation or stress relief, but it has been linked to rare cases of serious liver injury.
People with liver disease, heavy alcohol use, or those taking medications that affect the liver should exercise particular caution. Kava should also not be combined with sedatives or other calming medications without medical guidance.
Several herbal supplements are widely viewed as natural remedies, yet some have been linked to serious liver concerns. Here’s what you should know before using them.